tag:blogger.com,1999:blog-2741672436160438708.post4941455771392444567..comments2024-03-26T12:50:32.070-07:00Comments on Learning from and about cancer (chronic lymphocytic leukemia or CLL) by Dr. Brian Koffman: ASCO 2014: Dr. Susan O'Brien Outlines Open Trials of Novel Agents and Equipoise in Trial Design for CLL (chronic lymphocytic leukemia)Brian Koffmanhttp://www.blogger.com/profile/13250684684103918493noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-2741672436160438708.post-19367931708174732572014-12-05T08:53:40.365-08:002014-12-05T08:53:40.365-08:00I'm in the same situation as the person above....I'm in the same situation as the person above. I'm very close to treatment and all I hear is FCR or maybe just R but no promises on just R from my oncologist. He’s very conservative and he’s mentioned that numerous times. Finding a trial that accepts untreated folks is very limited or maybe I’m not looking in the right place. <br /><br />BUT wait, I do get it, the relapsed and refractory folks should come first because they have the most to gain in the trial. So where’s the untreated folks fall in ??? Do we need to go through the “rite of passage” down the chemo path first ??? Shouldn’t there be trials focused on first line therapies? Or are they out there and I don’t see them?<br /><br />One other question while I’m on my soapbox. What happens AFTER the trial? Say we get a good response from the drug and a relatively progression free life is obtained…is there a provision in these trails to remain on the drug at a reduced cost AFTER the trials. Is that normal or will the costs revert to what the market will bear?<br />Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-2741672436160438708.post-38001541427901760342014-12-04T08:33:10.382-08:002014-12-04T08:33:10.382-08:00Thanks for the quick post of the third segment Bri...Thanks for the quick post of the third segment Brian! Hope you enjoy SF and get some good info at ASH.<br /><br />With all the excitement over the past few years and keeping close to all the trial data, I was disheartened and a little shocked when my CLL doctor said I needed treatment (I am untreated) fairly soon and FCR would be at the top of the list for consideration. These agents are saving lives but sadly not yet much of a factor for untreateds with good markers.Anonymousnoreply@blogger.com